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Recent Publications


Sujan Gautam, Jennifer L Fenner, Boyuan Wang, Ryan C Range.  Evolutionarily conserved Wnt/Sp5 signaling is critical for anterior-posterior axis patterning in sea urchin embryos. iScience. 


MG Tassia, HA Hallowell, DS Waits, RC Range, CJ Lowe, RM Graze, EH Schwartz, KM Halanych. Induced Immune Reaction in the Acorn Worm, Saccoglossus kowalevskii, Informs the Evolution of Antiviral Immunity. Molecular Biology and Evolution. 


JG Ogilvie, S Van Belleghem, R Range, R Papa, OW McMillan, M. Chouteau, and BA Counterman. Balanced polymorphisms and their divergence in a Heliconius butterfly. Ecology and Evolution (2021). 

C Ka, S Gautam, SR Marshall, LP Tice, M Martinez-Bartolome, JL Fenner, RC Range. Receptor Tyrosine Kinases ror1/2 and ryk Are Co-expressed with Multiple Wnt Signaling Components During Early Development of Sea Urchin Embryos. The Biological Bulletin (2021).

F. Rodriguez-Caro, J. Fenner, S. Bhardwaj, J. Cole, C. Benson, A. M.Colombara, R. Papa, M. W. Brown, A. Martin, R. C. Range, B. A. Counterman. Novel Doublesex Duplication Associated with Sexually Dimorphic Development of Dogface Butterfly Wings. Molecular biology and evolution (2021).


Fenner J, Benson C, Rodriguez F, Ren A, Papa R, Hoffman F, Range RC, Counterman BA. “Wnt genes in wing pattern development of Coliadinae butterflies”. Frontiers in Ecology and Evolution (2020): 00197.


Martínez-Bartolomé, M., and Range, R. "A biphasic role of non-canonical Wnt16 signaling during early anterior-posterior patterning and morphogenesis of the sea urchin embryo". Development (2019). doi: 10.1242/dev.168799

Erkenbrack, E. M., Croce. J., Miranda, E., Gautam, S., Martínez-Bartolomé, M., Yaguchi, S., Range, R. C. “Whole mount in situ hybridization techniques for analysis of the spatial distribution of mRNAs in sea urchin embryos and early larvae”. Book Chapter. Methods in Cell Biology (2019).


Range, RC. "Canonical and non-canonical Wnt signaling pathways define the expression domains of Frizzled 5/8 and Frizzled 1/2/7 along the early anterior-posterior axis in sea urchin embryos". Developmental biology (2018).

Molina MD, Quirin M, Haillot E, De Grozé N, Range R, Rouel M, Jimenez F, Amrouche R, Chessel A, and Lepage T. "MAPK and GSK3/ß-TRCP-mediated degradation of the maternal Ets domain transcriptional repressor Yan/Tel controls the spatial expression of nodal in the sea urchin embryo". PLoS genetics 14.9 (2018): e1007621.

Khadka, A., Martínez-Bartolomé, M., Burr, S. D., Range, R. C. "A novel gene’s role in an ancient mechanism: secreted Frizzled-related protein 1 is a critical component in the Wnt signaling network governing anterior-posterior neuroectoderm patterning in sea urchin embryos". EvoDevo. (2018) 9:1,



Range, R. C., Martínez-Bartolomé, M., Burr, S. D. "The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions". J. Vis. Exp. (120), e55113, doi:10.3791/55113 (2017).


Range, Ryan C., and Zheng Wei. "An anterior signaling center patterns and sizes the anterior neuroectoderm of the sea urchin embryo." Development 143.9 (2016): 1523-1533.



Range, Ryan. "Specification and positioning of the anterior neuroectoderm in deuterostome embryos." genesis 52.3 (2014): 222-234.



Range RC, Angerer RC, and Angerer LA.  “Integration of canonical and non-canonical Wnt signaling patterns the neuroectoderm along the anterior-posterior axis of the sea urchin embryo”. PLoS Biology. 2013. 11(1): e1001467


Wei Z, Range R, Angerer R, and Angerer L. “Axial patterning interactions in the sea urchin embryo: suppression of nodal by Wnt1 signaling”. Development. 2012; 139(9): 1662-9.

Sethi AJ, Wikramanayake RM, Angerer RC, Range RC, and Angerer LA.  “Sequential signaling crosstalk regulates endomesoderm segregation in sea urchin embryos”. Science. 2012; 335(6068): 590-593.


Range R and Lepage T. “Maternal Oct1/2 is required for Nodal and Vg1/Univin expression during dorsal-ventral axis specification in the sea urchin embryo”. Developmental Biology. 2011; 17(10): 1487-98.

Croce J, Range R, Wu S, Miranda E, Lhomond G, Chieh-fu Peng J, Lepage T and McClay, DR.  “Wnt6 activates endoderm in the sea urchin gene regulatory network”. Development. 2011; 138: 3297-3306.


Saudemont A, Haillot E, Mekpoh F, Bessodes N, Quirin M, Lapraz F, Duboc V, Röttinger E, Range R, Oisel A, Besnardeau L, Wincker P, and Lepage T. “Gene regulatory network analysis of ectoderm specification in an echinoderm reveals ancestral regulatory circuits regulating mouth formation and neural induction”. PLoS Genetics. 2010. 6(12): e1001259.

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